abstract：:Liver dysfunction in hyperthyroid patients has not been well characterized. We analyzed the clinical records of 43 patients with hyperthyroidism to define the spectrum of clinical and liver test abnormalities. The patients were divided into three categories: (a) 18 patients with uncomplicated hyperthyroidism (HT) (b) ...

journal_title：Journal of clinical gastroenterology

authors： Fong TL,McHutchison JG,Reynolds TB

更新日期：1992-04-01 00:00:00

abstract：:We report two patients with the acquired immune deficiency syndrome and cytomegalovirus associated perianal ulcerations. Both complained of chronic, painful, nonhealing ulcers that required surgical intervention for diagnosis and palliation. One patient developed diffuse cytomegalovirus infection and both had poor res...

journal_title：Journal of clinical gastroenterology

authors： Kamel PL

更新日期：1992-03-01 00:00:00

abstract：:In advanced cirrhosis and hepatorenal syndrome, peripheral vasodilation is a prominent feature and may be pathophysiologically relevant. To determine whether the potent vasodilator, calcitonin gene-related peptide (CGRP), circulates at abnormal levels in patients with these disorders, we observed eight patients with a...

journal_title：Journal of clinical gastroenterology

authors： Gupta S,Morgan TR,Gordan GS

更新日期：1992-03-01 00:00:00

abstract：:A spontaneous intramural esophagogastric hematoma developed in a patient with hemophilia A. The hematoma did not resolve after antihemophiliac factor replacement but ruptured into the stomach causing massive gastrointestinal bleeding. The associated enlarged right tracheobronchial gland and the histopathological findi...

journal_title：Journal of clinical gastroenterology

authors： Intragumtornchai T,Israsena S,Benjacholamard V,Lerdlum S,Benjavongkulchai S

更新日期：1992-03-01 00:00:00

abstract：:A patient who presented with chronic inflammation of the colon, and initially also the terminal ileum, accompanied by marked diarrhea, is described. Repeated high-dose steroid therapy was only temporarily successful, and symptoms recurred upon dose reduction. During the further course of the disease, a marked elevatio...

journal_title：Journal of clinical gastroenterology

authors： Scheurlen M,Mörk H,Weber P

更新日期：1992-01-01 00:00:00

abstract：:Gastric cytoprotection in response to different agents (prostaglandins, carotenoids, etc.) failed to occur after surgical vagotomy. Decreased gastric emptying and the increased vascular permeability were tested in ethanol-treated rats without and with bilateral surgical vagotomy. The experiments were carried out on Sp...

journal_title：Journal of clinical gastroenterology

authors： Mózsik G,Király A,Garamszegi M,Jávor T,Nagy L,Németh A,Sütö G,Vincze A

更新日期：1992-01-01 00:00:00

abstract：:This study was designed to clarify the role of leukotrienes (LTs) in gastric injury induced by ischemia-reperfusion in rats. Gastric lesions were produced by clamping of the celiac artery and by reoxygenation following clamping. Administration of AA-861, a lipoxygenase inhibitor, significantly inhibited the increase i...

journal_title：Journal of clinical gastroenterology

authors： Yoshikawa T,Ichikawa H,Naito Y,Kondo M

更新日期：1992-01-01 00:00:00

abstract：:Between 1978 and 1989, 13 of 48 patients with anomalous union of the pancreaticobiliary ductal system (AUPBD) were diagnosed as having acute pancreatitis. We have studied the clinical, radiologic, and surgical features of these 13 patients. A transient rise in the intraductal pressure of the pancreatic duct during an ...

journal_title：Journal of clinical gastroenterology

authors： Mori K,Nagakawa T,Ohta T,Nakano T,Kadoya N,Kayahara M,Kanno M,Akiyama T,Ueno K,Konishi I

更新日期：1991-12-01 00:00:00

abstract：:Helicobacter pylori is absent in the antrum of approximately 5, 25, and 35% of patients with duodenal ulcer, gastric ulcer, and non-ulcer dyspepsia respectively and in the majority of asymptomatic healthy subjects from the West. The absence of H. pylori from the antrum could result from failure of exposure to (Group A...

journal_title：Journal of clinical gastroenterology

authors： Desai HG,Gill HH

更新日期：1991-10-01 00:00:00

abstract：:Gastrin stimulates the growth of some human colon adenocarcinomas grown in vitro or as xenografts in nude mice. To evaluate the possibility of elevated plasma gastrin levels in patients with adenomatous polyps or colorectal cancer, we carried out a radioimmunoassay in subjects fasting overnight and undergoing colonosc...

journal_title：Journal of clinical gastroenterology

authors： Seitz JF,Giovannini M,Gouvernet J,Gauthier AP

更新日期：1991-10-01 00:00:00

abstract：:To avoid the two pitfalls of medicine, it is essential to maintain the distinction between "functional disorders" and "organic diseases." Medicalization consists in forgetting the suffering of a patient and focusing on a sick organ. This is incorrect scientifically, because it dismisses the complexity of science by de...

journal_title：Journal of clinical gastroenterology

authors： Devroede G

更新日期：1991-10-01 00:00:00

abstract：:Using an elevated serum amylase level to diagnose acute pancreatitis in an alcoholic patient with abdominal pain may not be appropriate, because hyperamylesemia is common in asymptomatic alcoholics without acute pancreatitis. To determine whether serum lipase also suffers from the same drawback, we undertook a prospec...

journal_title：Journal of clinical gastroenterology

authors： Gumaste VV,Sereny G,Dave P,Bhardwaj A,Gumaste S

更新日期：1991-08-01 00:00:00

abstract：:Esophageal intramural pseudodiverticulosis (EIP) is a rare disease, characterized by multiple, small flask-shaped diverticula in the esophageal wall, and best demonstrated on single-contrast barium examination. Though the condition is often associated with reflux esophagitis, Candida esophagitis, and esophageal dysmot...

journal_title：Journal of clinical gastroenterology

authors： Kochhar R,Mehta SK,Nagi B,Goenka MK

更新日期：1991-08-01 00:00:00

abstract：:We describe a 33-year-old man with giant hypertrophic gastropathy (Menetrier's disease), which, on operative biopsy of the stomach, showed a significant inflammatory component. The patient was treated with prednisone and quickly responded. Although a review of the literature revealed only two cases similarly treated, ...

journal_title：Journal of clinical gastroenterology

authors： Davis GE,O'Rourke MC,Metz JR,Kindig WV,Sweeney JG,Kane KN

更新日期：1991-08-01 00:00:00

abstract：:We report a 29-year-old woman with a 20-year history of Crohn's disease and neutropenia. Because of repeated complications of Crohn's disease, she has undergone three intestinal resections and also has had recurrent skin abscesses, sinusitis, and pneumonia. Persistent neutropenia has been noted throughout the course o...

journal_title：Journal of clinical gastroenterology

authors： Stevens C,Peppercorn MA,Grand RJ

更新日期：1991-06-01 00:00:00

abstract：:Non-A, non-B viral hepatitis may cause many different hematologic abnormalities, such as transient anemia, granulocytopenia, thrombocytopenia, atypical lymphcytosis, or aplastic anemia. We describe a patient who developed a myelodysplastic syndrome (refractory anemia with excess blasts) after prednisone therapy for no...

journal_title：Journal of clinical gastroenterology

authors： Jacoby RF,Brasitus TA

更新日期：1991-04-01 00:00:00

abstract：:We documented the natural history of esophageal carcinoma and its rapid growth by measuring the change in tumor diameter radiographically in 10 patients during an observation period because the diagnosis had been missed. Nine men and one woman (age range, 48-74 years; mean, 60 years) were included in the study. Eight ...

journal_title：Journal of clinical gastroenterology

authors： Haruma K,Tokutomi T,Yoshihara M,Sumii K,Kajiyama G

更新日期：1991-04-01 00:00:00

abstract：:We describe the clinical features, liver histology, and ultrastructure in reversible diclofenac-induced hepatitis and review previous reports of this entity. Although rarely reported, diclofenac hepatitis may be severe, and even fatal. Symptoms, which develop from 1 week to 11 months after starting the drug, include j...

journal_title：Journal of clinical gastroenterology

authors： Ouellette GS,Slitzky BE,Gates JA,Lagarde S,West AB

更新日期：1991-04-01 00:00:00

abstract：:Abnormalities in esophageal peristaltic function and acid clearance appear to be responsible for prolonged esophageal acid exposure, a major determinant of the reflux esophagitis and esophageal stricture. We evaluated esophageal motility by manometry in 50 healthy controls and in 35 symptomatic reflux patients before,...

journal_title：Journal of clinical gastroenterology

authors： Grande L,Lacima G,Ros E,Pujol A,Garcia-Valdecasas JC,Fuster J,Visa J,Pera C

更新日期：1991-02-01 00:00:00

abstract：:We report four new cases of oral manifestation in Crohn's disease (CD) and evaluate 75 reported cases for morphology and site of oral and intestinal manifestations of CD, clinical manifestation, and treatment. Oral CD was the presenting symptom in 43 of 72 (60%) patients and relapsed in 34 of 60 (57%). Median age at p...

journal_title：Journal of clinical gastroenterology

authors： Plauth M,Jenss H,Meyle J

更新日期：1991-02-01 00:00:00

abstract：:Disposable biopsy forceps have recently been introduced into the field of endoscopy. We have analyzed biopsy size and histologic interpretation of samples obtained with the disposable forceps and compared them to those obtained with reusable forceps. In the 18 patients studied, 49 samples were collected with the reusa...

journal_title：Journal of clinical gastroenterology

authors： Turk DJ,Kozarek RA,Botoman VA,Patterson DJ,Ball TJ

更新日期：1991-02-01 00:00:00

abstract：:One hundred outpatients with endoscopically verified duodenal ulcer were treated in a double-blind, randomized, multicenter trial with either low-dose antacid (AA, Supralox, 1 tablet three times a day 1 h a.c. and 2 tablets at bedtime, with acid binding capacity of 225 mEq) or misoprostol (MS, Cytotec, 400 micrograms ...

journal_title：Journal of clinical gastroenterology

authors： Nauert C,Caspary WF

更新日期：1991-01-01 00:00:00

abstract：:A great deal is known about methods to diminish intragastric acid concentration, but far less is known about the ability of the gastroduodenal mucosa to resist injury or accelerate its healing. One group of compounds that plays a key role in the endogenous ability of the mucosa to protect itself against injury and per...

journal_title：Journal of clinical gastroenterology

authors： Hollander D,Tarnawski A

更新日期：1991-01-01 00:00:00

abstract：:Antacids have been used as remedies for benign gastroduodenal disorders for centuries. They were regarded to be effective in relieving gastric pain and symptoms of hyperacidity and in promoting ulcer healing. The effectiveness was based on empiric observations and was not derived from the controlled clinical trials da...

journal_title：Journal of clinical gastroenterology

authors： Sewing KF

更新日期：1991-01-01 00:00:00

abstract：:This article emphasizes and reviews the premise that because the pathogenesis of acute gastric mucosal injury is multifactorial, several protective mechanisms should also be considered in analyzing gastric mucosal defense. The first part of the article reviews the pathogenesis of acute gastric mucosal injury by major ...

journal_title：Journal of clinical gastroenterology

authors： Szabo S

更新日期：1991-01-01 00:00:00

abstract：:Supplements consisting primarily of dietary fibers are marketed as aids to weight reduction. Of uncertain efficacy, they have generally been regarded as safe when used according to directions. We report two cases of acute esophageal obstruction by a guar gum product in patients with preexisting esophageal abnormalitie...

journal_title：Journal of clinical gastroenterology

authors： Opper FH,Isaacs KL,Warshauer DM

更新日期：1990-12-01 00:00:00

abstract：:To test our hypothesis that the erythrocytic sedimentation rate (ESR) correlates well with clinical activity in inflammatory disease of the colon, but not of the small bowel, we stratified 49 Crohn's disease patients according to their anatomic involvement and then measured the correlations between ESR and clinical ac...

journal_title：Journal of clinical gastroenterology

authors： Sachar DB,Luppescu NE,Bodian C,Shlien RD,Fabry TL,Gumaste VV

更新日期：1990-12-01 00:00:00

abstract：:Chylous ascites remains rare as a complication of surgical intervention. Although therapeutic manoeuvres to control chylous ascites have been developed over the past 20 years, its pathophysiology is poorly understood. Conservative approaches involving dietary restriction of long-chain triglycerides and salt, together ...

journal_title：Journal of clinical gastroenterology

authors： Ohri SK,Patel T,Desa LA,Spencer J

更新日期：1990-12-01 00:00:00

abstract：:Islet cell carcinoma frequently produces more than one chemical product, although its clinical expression is usually restricted to a single hormone. We describe an unusual patient who presented with full-blown metastasizing gastrinoma. He was treated with cimetidine for five years and then streptozotocin therapy, whic...

journal_title：Journal of clinical gastroenterology

authors： Bar M,Burke M,Isakov A,Almog C

更新日期：1990-10-01 00:00:00

abstract：:Crohn's disease (CD) is now accepted as a systemic illness. The importance of extraintestinal manifestations is underlined by the fact that such "complications" can be more prominent and even more difficult to control than the intestinal disease itself. Lately, evidence for a more than accidental association of pancre...

journal_title：Journal of clinical gastroenterology

authors： Piontek M,Hengels KJ,Strohmeyer G

更新日期：1990-10-01 00:00:00

abstract：:We identified spontaneous reactivation of hepatitis B virus (HBV) retrospectively by utilizing serum alanine aminotransferase and HBV DNA in 19 men (79% homosexual), with an estimated annual incidence of 7.3%. In 11 patients, spontaneous reactivation occurred as a single episode and in eight patients, reactivation was...

journal_title：Journal of clinical gastroenterology

authors： Gupta S,Govindarajan S,Fong TL,Redeker AG

更新日期：1990-10-01 00:00:00

abstract：:Repeated surgical interventions on the biliary ductal system increase morbidity and mortality, particularly in the geriatric patient. In an attempt to prevent these complications, side-to-side choledochoduodenostomy was performed as the primary operative procedure in 54 patients, age 72 +/- 13 years. This was the pati...

journal_title：Journal of clinical gastroenterology

authors： Berlatzky Y,Freund HR

更新日期：1990-08-01 00:00:00

abstract：:Two patients with similar symptoms referred for diagnosis and treatment of hepatic failure subsequently proved to have cardiomyopathy as the cause of their hepatic decompensation. Except for fatigue and edema, symptoms of congestive heart failure were absent and no history of dyspnea, orthopnea, or paroxysmal nocturna...

journal_title：Journal of clinical gastroenterology

authors： Hoffman BJ,Pate MB,Marsh WH,Lee WM

更新日期：1990-06-01 00:00:00

abstract：:Aspirin is commonly accepted as a risk factor for gastric ulcer; however, there is little published evidence linking aspirin consumption to duodenal ulcer. The effect of 1 g of aspirin per day on site-specific ulcer hospitalizations was examined using data from a 3-year randomized, double-blind, placebo-controlled tri...

journal_title：Journal of clinical gastroenterology

authors： Kurata JH,Abbey DE

更新日期：1990-06-01 00:00:00

abstract：:We observed jejunal water and sodium secretion in two patients with chronic idiopathic intestinal pseudo-obstruction by standard perfusion techniques. The ability of glucose to reverse this secretory state was impaired. These observations suggest that a jejunal secretory state may contribute to the diarrhea in chronic...

journal_title：Journal of clinical gastroenterology

authors： Rolston DD,Hunt JB,Fairclough PD,Wilks M,Levison DA,Clark ML,Farthing MJ

更新日期：1990-04-01 00:00:00

abstract：:We report a patient with classical features of amiodarone hepatotoxicity who died of progressive liver failure. Throughout the course of his illness, he had epigastric pain, nausea, vomiting, and persistent mild to moderate elevation of amylase and lipase in his serum and peritoneal fluid. Pancreatitis due to amiodaro...

journal_title：Journal of clinical gastroenterology

authors： Sastri SV,Diaz-Arias AA,Marshall JB

更新日期：1990-02-01 00:00:00

abstract：:In a Chinese family with hereditary pancreatitis, two members are proven to have chronic pancreatitis. The propositus, a 31-year-old man, had epigastric pain since the age of 18. Multiple calcifications in the region of the pancreas were seen on plain film of the abdomen, ultrasonography, computed tomography, and endo...

journal_title：Journal of clinical gastroenterology

authors： Lin JT,Wang TH,Chen DS

更新日期：1990-02-01 00:00:00

abstract：:In a double-blind placebo-controlled study, we examined the effect of calcitonin on gastric emptying, and on serum concentrations of gastrin, insulin, glucose, calcium, and phosphorus after a mixed solid-liquid meal in 11 healthy men. Synthetic salmon calcitonin was administered as a 415 pmol i.v. bolus injection foll...

journal_title：Journal of clinical gastroenterology

authors： Jonderko K,Jonderko G,Gołab T

更新日期：1990-02-01 00:00:00

abstract：:The present study was designed to assess histologic and ultrastructural features of gastric mucosa in the areas of grossly healed ulcers (acetic acid-induced gastric ulcers) in rats. The specific question we studied was whether the structure and cellular composition of the gastric mucosa in an area of grossly healed u...

journal_title：Journal of clinical gastroenterology

authors： Tarnawski A,Hollander D,Krause WJ,Dabros W,Stachura J,Gergely H

更新日期：1990-01-01 00:00:00

abstract：:The glycosphingolipid (GSL) compositions of the human, rabbit, and rat gastric mucosa were studied and compared. In neutral GSLs, although GalCer was the most abundant component in every tissue examined, species-specific differences were clearly observed in their composition. Acidic GSLs were composed of sulfatides an...

journal_title：Journal of clinical gastroenterology

authors： Natomi H,Sugano K,Takaku F,Iwamori M

更新日期：1990-01-01 00:00:00